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Recent Advances in the Cycloaddition Chemistry of Isomünchnones and Thioisomünchnones, an Under-Utilized Class of Mesoionic Compounds
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1994
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Combinatorial ChemistryEngineeringHeterocyclicFunctionalized LactamsNatural Product SynthesesMesoionic CompoundsOrganic ChemistryCycloaddition ChemistrySynthetic ChemistryChemistryHeterocycle ChemistryPharmacologyRecent AdvancesEnantioselective SynthesisBiomolecular EngineeringNatural Product Synthesis
This review describes the methods of preparation and use of isomunchnones and thioisomunchnones to synthesize furans, 2-pyridones, functionalized lactams and other heterocyclic ring systems. Some promising intramolecular dipolar cycloadditions of these mesoionic compounds, and their potential for natural product syntheses, are presented