Asymmetric Organocatalytic Synthesis of <i>cis</i>-Substituted Dihydrobenzofuranols via Intramolecular Aldol Reactions

Abstract

The diastereo- and enantioselective synthesis of 3-hydroxy 2,3-dihydrobenzofurans via an intramolecular cis-selective aldol reaction employing proline-type organocatalysts is described enabling a new entry to coumarine natural products.