Synlett · 2004 · 31 citations · 0 references
Natural SciencesChemical EngineeringChemistryCatalysisOrganic ChemistryReaction EngineeringCatalyst DesignCatalyst PreparationCatalyst SynthesisIndustrial Catalytic ProcessesOrganic SynthesisSolvent-free SynthesisCatalyst Development For SynthesisCatalytic SynthesisSupported Acid Catalysts
Sulphamic acid (H2NSO3H, SA) is used as an alternative to conventional acid catalysts in the Pechmann condensation of phenols with β-ketoester leading to the formation of substituted coumarin. The method is simple, cost-effective, solvent-free and gives good yields in a short reaction time.