Microwave Assisted Synthesis of 1-Aryl-3-dimethylaminoprop-2-enones: A Simple and Rapid Access to 3(5)-Arylpyrazoles

Abstract

Condensation of aromatic acyl compounds with N,N-dimethylformamide diethyl acetal in a pressure tube under microwave heating gives 1-aryl-3-dimethylaminoprop-2-enones in almost quantitative yields. In the presence of hydrazine, these intermediates are transferred to the corresponding 3-arylpyrazoles.