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Catalytic Arylations with Challenging Substrates: From Air-Stable HASPO Preligands to Indole Syntheses and C-H-Bond Functionalizations

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2007

Year

Abstract

The development of novel ligands and their applications to transition-metal catalysis performed in our laboratory are ­summarized. These studies include the use of air-stable, modular heteroatom-substituted secondary phosphine oxides (HASPO) in cross-coupling reactions of challenging substrates, such as aryl and vinyl chlorides, fluorides, and tosylates.