Reagent and Catalyst Design for Asymmetric Hypervalent Iodine Oxidations

Abstract

In this review are compiled the different possible transformations using environmentally benign chiral hypervalent iodine reagents and catalysts. Herein is presented an overview of asymmetric oxidation of sulfides to sulfoxides, oxidation of alkenes, α-functionalization of carbonyl compounds and dearomatization reactions. 1 Introduction 2 Chiral Hypervalent Iodine Reagents 3 Oxidation of Sulfides to Sulfoxides 4 Oxidation of Alkenes 5 α-Functionalization of Carbonyl Compounds 6 Dearomatization Reactions 7 Conclusion