Heterocycles · 2006 · 81 citations · 5 references
Natural SciencesChemical EngineeringChemistryCatalysisOrganic ChemistryReaction EngineeringCatalyst DesignCatalyst PreparationCatalyst SynthesisCatalytic MaterialsCatalytic MechanismsCatalytic Reaction EngineeringAldehydesBenzimidazole ChemistryBenzimidazole SynthesisCatalyst Development For SynthesisRoom-temperature Synthesis
Sulfamic acid, an eco-friendly and zwitterionic solid, proved to be a very efficient catalyst for the reaction of ortho-phenylenediamine with aryl aldehydes in ethanol at room temperature to furnish both 1-arylmethyl-2-aryl-and 2-arylbenzimidazoles in very good to excellent overall yields.
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