Publication | Open Access
Phosphoric Acid-on-Silica Gel: A Green Catalyst for the Synthesis of Symmetrical Bis(indolyl)alkanes
29
Citations
37
References
2006
Year
Chemical EngineeringSymmetrical BisGreen CatalystOrthophosphoric AcidEngineeringNatural SciencesTlc-grade Silica GelDiversity-oriented SynthesisGreen ChemistryOrganic ChemistryCatalysisPhosphoric Acid-on-silica GelChemistryCatalyst PreparationHomogeneous CatalysisMolecular CatalysisSynthetic ChemistryCatalytic Synthesis
Orthophosphoric acid, adsorbed on TLC-grade silica gel, has been demonstrated to be an efficient green catalyst for an expeditious and solvent-free one-step synthesis of symmetrical bis(indolyl)alkanes from the reaction of indoles with aryl aldehydes at 60-70 °C.
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