Carbohydrate‐Substituted Triarylphosphanes— A New Class of Ligands for Two‐Phase Catalysis

Abstract

Two-phase catalysts with sugar-substituted ligands, such as glycoside–triarylphosphanes 1 a–c, reveal advantages over catalysts with the classical TPPTS ligands in Heck and Suzuki reactions. A simple and generally applicable synthesis has been developed for this new class of neutral, hydrophilic ligands. On account of thermoreversible solvation, the concentration of the two-phase catalyst in the nonpolar medium increases with increasing temperature, as shown by the Nernst distribution coefficient determined for one of the new ligands at different temperatures.