Highly Functionalized and Stereocontrolled Syntheses of 2-(2-Methylenecycloalkyl)-furan Derivatives by Pd-Catalyzed Cycloreduction

Abstract

[structure: see text]. We have discovered a new method employing Pd-catalyzed cycloreduction of conjugated enynals 1 bearing an alkyne unit leading to the corresponding 2-(2-methylenecycloalkyl)-furans 2a-j and a related compound 7 in good to excellent yields.