Reactivity of cyanothioformamides and 3‐(4‐bromophenyl)‐5‐imino‐4‐oxazolidinethione toward ortho‐substituted nucleophiles

Abstract

Abstract The substituted benzoazoles 4 and 5a,b were obtained by the reaction of cyanothioformamides 1d and 1b or 1c with o‐substituted aromatic amines 2b and 2c , respectively. Fused pyrimidinones 10, 12 , and 14 were synthesized by the reaction of oxazolidinethione ( 9 ) with 2‐amino aromatic and heteroaromatic carboxylic acids. The structures of the synthesized compounds were established based on elemental analysis and spectral data studies. © 2002 Wiley Periodicals, Inc. Heteroatom Chem 13:611–616, 2002; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10042