Enantioselective Synthesis of 3,6-Dihydro-1<i>H</i>-pyridin-2-ones: Unexpected Regioselectivity in the Palladium-Catalyzed Decarboxylative Carbonylation of 5-Vinyloxazolidin-2-ones

Abstract

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTEnantioselective Synthesis of 3,6-Dihydro-1H-pyridin-2-ones: Unexpected Regioselectivity in the Palladium-Catalyzed Decarboxylative Carbonylation of 5-Vinyloxazolidin-2-onesJulian G. Knight, Simon W. Ainge, Andrew M. Harm, Simon J. Harwood, Haydn I. Maughan, Duncan R. Armour, David M. Hollinshead, and Albert A. Jaxa-ChamiecView Author Information Department of Chemistry, Bedson Building Newcastle University Newcastle upon Tyne, NE1 7RU, UK GlaxoWellcome Medicines Research Centre, Gunnels Wood Road Stevenage, Hertfordshire, SG1 2NY, UK Zeneca Pharmaceuticals, Mereside, Alderley Park Macclesfield, Cheshire, SK10 4TG, UK Cite this: J. Am. Chem. Soc. 2000, 122, 12, 2944–2945Publication Date (Web):March 10, 2000Publication History Received3 November 1999Published online10 March 2000Published inissue 1 March 2000https://pubs.acs.org/doi/10.1021/ja993897chttps://doi.org/10.1021/ja993897crapid-communicationACS PublicationsCopyright © 2000 American Chemical SocietyRequest reuse permissionsArticle Views1641Altmetric-Citations67LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Amides,Carbonylation,Ethanol,Palladium,Substitution reactions Get e-Alerts