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One-pot Synthesis of Aryl Sulfones from Alcohols
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2002
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EngineeringOne-pot SynthesisOrganic ChemistryCatalysisStereoselective SynthesisChemistryPrimary AlcoholsSynthesis MethodNatural Product SynthesisSynthetic ChemistryEnantioselective SynthesisAryl Sulfones
A one-pot synthesis of aryl sulfones from primary alcohols is described. Alcohols were treated with N-bromosuccinimide and triphenylphosphine, followed by addition of sodium arenesulfinate with a catalytic amount of tetrabutylammonium iodide to afford the aryl sulfones in good to high yields.