Concepedia

Di-µ-Hydroxy-bis(N,N,N′,N′-tetramethylenediamine)copper(II) Chloride {[Cu(OH)˙TMEDA]2Cl2} Catalyzed Tandem Phosphorous-Carbon Bond Formation-Oxyfunctionalization: Efficient Synthesis of Phenacyl Tertiary [nl]Phosphine-Boranes

Gullapalli Kumaraswamy, Gadde Venkata Rao, A. R. V. MURTHY, Balasubramanian Sridhar

Synlett · 2009 · 17 citations · 0 references

Concepts

Natural SciencesChemistryCatalysisOrganic ChemistryOrganometallic ChemistryCoordination ChemistryCross-coupling ReactionsOrganic SynthesisOrganometallic SynthesisC - C Coupling CatalysisCopper CatalysisCopper-catalyzed CouplingLate-stage Functionalization Via Cross-couplingTandem CatalysisTandem ReactionsTransition Metal-catalyzed SynthesisTransition-metal-catalyzed Functionalization

Abstract

A novel [Cu(OH)˙TMEDA]2Cl2 catalyzed tandem reaction has been developed for the synthesis of a series of sterically and electronically divergent phenacyl tertiary phosphine-boranes.