Titanocene-Catalyzed Conjugate Reduction of α,β-Unsaturated Carbonyl Derivatives

Abstract

A titanocene-catalyzed conjugate reduction of alpha,beta-unsaturated carbonyl derivatives has been developed. A series of carbonyl compounds including aldehydes, ketones, esters, and amides proved viable in the reduction process providing an efficient, chemoselective method for the catalytic reduction of unsaturated carbonyl derivatives.