Concepedia

Haematocin, a New Antifungal Diketopiperazine Produced by Nectria haematococca Berk. et Br. (880701a-1) Causing Nectria Blight Disease on Ornamental Plants.

Yoshikatsu Suzuki, Hiroshi Takahashi, Yasuaki Esumi, Tsutomu Arie, Tetsuichiro Morita, Hiroyuki Koshino, Jun Uzawa, Masakazu Uramoto, Isamu Yamaguchi

The Journal of Antibiotics · 2000 · 23 citations · 3 references

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Abstract

A new antifungal diketopiperazine named haematocin was isolated from the culture broth of Nectria haematococca Berk. et Br. (880701a-1) causing blight disease on ornamental plants, Phalaenopsis spp. and Doritanopsis spp. Its structure was established by spectroscopic methods. Haematocin inhibited the germ-tube elongation and spore-germination of Pyricularia oryzae at the ED50 values of 30 microg/ml and 160 microg/ml, respectively.

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