Total Synthesis and Preliminary Antibacterial Evaluation of the RNA Polymerase Inhibitors (±)-Myxopyronin A and B

Abstract

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTTotal Synthesis and Preliminary Antibacterial Evaluation of the RNA Polymerase Inhibitors (±)-Myxopyronin A and BTao Hu, Jennifer V. Schaus, Kelvin Lam, Michael G. Palfreyman, Mark Wuonola, Gary Gustafson, and James S. PanekView Author Information Department of Chemistry, Metcalf Center for Science and Engineering, 590 Commonwealth Avenue, Boston University, Boston, Massachusetts 02215 and Scriptgen Pharmaceuticals Inc., 200 Boston Avenue, Medford, Massachusetts 02155 Cite this: J. Org. Chem. 1998, 63, 7, 2401–2406Publication Date (Web):March 12, 1998Publication History Received9 December 1997Published online12 March 1998Published inissue 1 April 1998https://pubs.acs.org/doi/10.1021/jo9721610https://doi.org/10.1021/jo9721610brief-reportACS PublicationsCopyright © 1998 American Chemical SocietyRequest reuse permissionsArticle Views1823Altmetric-Citations36LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Aldehydes,Bacteria,Genetics,Organic compounds,Peptides and proteins Get e-Alerts