Impact of age and renal function on usefulness of NT-proBNP to diagnose heart failure

Xavier Charmetant, Matthieu Pecquet, P. Poirié, Danièle Agi, Jean‐François Aupetit, Emmanuel Villar

Clinical Nephrology · 2019 · 15 citations · 0 references

Concepts

Abstract

AIMS: NT-proBNP is a useful biomarker for heart failure (HF) diagnosis. We aimed to determine NT-proBNP's ability to diagnose HF by age and renal function. MATERIALS AND METHODS: We analyzed 3,699 consecutive and unique adults admitted for dyspnea at the Emergency Unit of St. Joseph St. Luc Hospital, Lyon, France, from December 1, 2012 to June 30, 2016, who had concomitant measurement of NT-proBNP and serum creatinine. We excluded patients with acute coronary syndrome and dialysis patients. Receiving operating characteristic (ROC) analysis assessed ability and cut-off points of NT-proBNP to diagnose HF. RESULTS: ;. CONCLUSION: remains uncertain.