Concepedia

Total Synthesis of (±)-Dysibetaine

Jerry Isaacson, Mandy Loo, Yoshihisa Kobayashi

Organic Letters · 2008 · 37 citations · 8 references

DOI

Concepts

Abstract

The marine natural product dysibetaine was synthesized in racemic form from a levulinic acid derivative using a convertible isocyanide and an ammonium acetate in the Ugi 4-center-3-component condensation reaction.

References

8

An improved catalytic OsO4 oxidation of olefins to -1,2-glycols using tertiary amine oxides as the oxidant

V. VanRheenen, Robert C. Kelly · Tetrahedron Letters · 1976 · 1K citations

, , +10

New Entry to Convertible Isocyanides for the Ugi Reaction and Its Application to the Stereocontrolled Formal Total Synthesis of the Proteasome Inhibitor Omuralide

Cynthia B. Gilley, Matthew J. Buller, Yoshihisa Kobayashi · Organic Letters · 2007 · 95 citations

, , +17

Multi-component reactions 13: Synthesis of γ-lactams as part of a multiring system via Ugi-4-centre-3-component reaction

Cordelia Hanusch-Kompa, Ivar Ugi · Tetrahedron Letters · 1998 · 81 citations

, , +8

Ozonolysis of trans-2,3-dichloro-2-butene. Isolation of .alpha.-chloro peroxides

Karl Griesbaum, Peter Hofmann · Journal of the American Chemical Society · 1976 · 44 citations

, , +6

Structure-Reactivity Relationship in the Reaction of Highly Reactive Zinc with Alkyl Bromides

Albert Guijarro, Reuben D. Rieke · Angewandte Chemie International Edition · 1998 · 40 citations

, , +10