Synthesis · 1990 · 10 citations · 0 references
Acid ConditionsEngineeringBiochemistryNatural Sciencesα-Hydroxy ButyrolactonesOrganic ChemistryStereoselective SynthesisChemistryα-Oxocarboxylic Acids ReactSynthetic ChemistryEnantioselective SynthesisBiomolecular EngineeringNatural Product Synthesis
α-Oxocarboxylic acids react with olefins under acid conditions to give α-hydroxy butyrolactones (3-hydroxy-2-oxotetrahydrofurans) which can be readily dehydrated to give α,β-unsaturated butyrolactones 2-oxo-2,5-dihydrofurans.