European Journal of Organic Chemistry · 2001 · 12 citations · 0 references
Natural SciencesChemistryMedicinal ChemistryOrganic ChemistrySynthetic Medicinal ChemistryOrganic SynthesisDouble Bond ConfigurationDouble Bond Position AnalysisRing-forming Reactions
New convenient syntheses of 3-carboxycephems starting from 7-ACA are reported. All three possible cephem derivatives with respect to the position of the double bond in the six-membered ring and oxidation state of the sulfur atom have been synthesized in high overall yield.