<i>N</i>-Heterocyclic Carbene Catalyzed Domino Cyclization of Propargylic Alcohols and Benzoyl Isocyanates

Kyoung A Jo, Muchchintala Maheswara, Eunyoung Yoon, Yun Yeong Lee, Hoseop Yun, Eun Joo Kang

The Journal of Organic Chemistry · 2012 · 35 citations · 39 references

Concepts

Abstract

N-Hetereocyclic carbenes (NHCs) were found to be efficient catalysts for the cyclization of propargylic alcohols and isocyanates. Domino cyclization reactions were carried out using isopropyl-substituted imidazolium salt as a precatalyst, and a wide range of substituted oxazolidinones were obtained in high yields.

References

39