Recent Advances in Palladium-Catalyzed C(sp3)–H Activation for the Formation of Carbon–Carbon and Carbon–Heteroatom Bonds

Abstract

Within this review, recent developments in the field of C(sp³)–H activation catalyzed by palladium are discussed. Both intra­- and intermolecular reactions towards carbon–carbon and carbon–heteroatom bonds are covered. In the case of intramolecular reactions­, asymmetric versions are reported as well. The main focus of this review is literature of the last five years until late 2013. 1 Introduction 2 Intramolecular C(sp³)–H Activation 2.1 Carbon–Carbon Coupling 2.2 Carbon–Heteroatom Coupling 2.3 Stereoselective Reactions 3 Intermolecular C(sp³)–H Activation 3.1 Carbon–Carbon Coupling 3.2 Carbon–Heteroatom Coupling 4 Conclusion and Outlook