Insight into the antitumor activity of carbosilane Cu(<scp>ii</scp>)–metallodendrimers through their interaction with biological membrane models

Natalia Sanz del Olmo, Riccardo Carloni, Ana M. Bajo, Paula Ortega, Alberto Fattori, Rafael Gómez, M. Francesca Ottaviani, Sandra García‐Gallego, Michela Cangiotti, F. Javier de la Mata

Nanoscale · 2019 · 37 citations · 24 references

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Abstract

was selected for in-depth in vitro and in vivo antitumor evaluation towards resistant prostate cancer. The Cu(ii)-metallodendrimers produced a significant tumor size reduction with no signs of toxicity during the experiment, confirming their promising potential as anticancer metallodrugs.

References

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