New environmentally friendly solvent free synthesis of dihydropyrimidinones catalysed by N-butyl-N,N-dimethyl-α-phenylethylammonium bromide

100 years of the biginelli dihydropyrimidine synthesis

C. Oliver Kappe · Tetrahedron · 1993 · 1.2K citations

Natural Sciences, Chemistry, Medicinal Chemistry +8

Calcium Entry Blockers and Activators: Conformational and Structural Determinants of Dihydropyrimidine Calcium Channel Modulators

George C. Rovnyak, S. David Kimball, Barbara Beyer et al. · Journal of Medicinal Chemistry · 1995 · 549 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Unprecedented Catalytic Three Component One-Pot Condensation Reaction:  An Efficient Synthesis of 5-Alkoxycarbonyl- 4-aryl-3,4-dihydropyrimidin-2(1H)-ones

Essa Hu, Daniel R. Sidler, Ulf‐H. Dolling · The Journal of Organic Chemistry · 1998 · 501 citations

Natural Sciences, Chemistry, Catalysis +6

Indium(III) Chloride-Catalyzed One-Pot Synthesis of Dihydropyrimidinones by a Three-Component Coupling of 1,3-Dicarbonyl Compounds, Aldehydes, and Urea: An Improved Procedure for the Biginelli Reaction

Brindaban C. Ranu, Alakananda Hajra, Umasish Jana · The Journal of Organic Chemistry · 2000 · 474 citations

Natural Sciences, Chemistry, Catalysis +5

Conformational analysis of 4-aryl-dihydropyrimidine calcium channel modulators. A comparison of ab initio, semiempirical and X-ray crystallographic studies

C. Oliver Kappe, Walter M. F. Fabian, M.A. Semones · Tetrahedron · 1997 · 402 citations

Natural Sciences, Chemistry, Medicinal Chemistry +17