A convenient synthesis of chiral peptide nucleic acid (PNA) monomers

Sequence-Selective Recognition of DNA by Strand Displacement with a Thymine-Substituted Polyamide

Peter E. Nielsen, Rolf H. Berg, Ole Buchardt · Science · 1991 · 3.3K citations

Life Sciences, Biomolecular Engineering, Molecular Biology +17

Peptide nucleic acids (PNA). Oligonucleotide analogs with an achiral peptide backbone

Ole Buchardt, Peter E. Nielsen, Rolf H. Berg · Journal of the American Chemical Society · 1992 · 736 citations

Life Sciences, Biochemistry, Molecular Biology +12

Highly active and selective anticoagulants: D-Phe-Pro-Arg-H, a free tripeptide aldehyde prone to spontaneous inactivation, and its stable N-methyl derivative, D-MePhe-Pro-Arg-H

S. Bajusz, E. Széll, D Bagdy et al. · Journal of Medicinal Chemistry · 1990 · 170 citations

Medicine, Biochemistry, Pharmacology +17

Phosphorothioate and normal oligodeoxyribonucleotides with 5′-linked acridine: characterization and preliminary kinetics of cellular uptake

C.A. Stein, Kazuyo Mori, S.L. Loke et al. · Gene · 1988 · 122 citations

Life Sciences, Biochemistry, Molecular Biology +8

Synthesis of a potent, reversible inhibitor of interleukin-1β converting enzyme

Kevin T. Chapman · Bioorganic & Medicinal Chemistry Letters · 1992 · 83 citations

Medicine, Medicinal Chemistry, Pharmacology +11