Concepedia

<i>α</i>-Oxygen-atom Induced Methylenation of Ketones by CH<sub>2</sub>(ZnI)<sub>2</sub>

Katsumi Ukai, Daisuke Arioka, Hideaki Yoshino, Hideo Fushini, Koichiro Oshima, Kiitiro Utinoto, Seijiro Matsubara

Synlett · 2001 · 15 citations · 0 references

DOI

Concepts

Abstract

Ketones bearing a hetero-atom at α-position were methylenated selectively by CH2(ZnI)2 to give allylic alcohols; a nucleophilic attack of the zinc species was accelerated with a coordination of a hetero-atom at α-position.