Visible Light‐Induced Regioselective Decarboxylative Alkylation of the C(<i>sp</i>²)−H Bonds of Non‐Aromatic Heterocycles

Abstract

Abstract With sunlight or blue LEDs irradiation, regioselective decarboxylative alkylation of various non‐aromatic heterocycles has been realized via C( sp 3 )‐centered radical C( sp 2 )−C( sp 3 ) bond formation under oxidant‐free conditions at room temperature. This reaction readily incorporates various functional alkyl groups into heterocyclic compounds without observation of any alkyl radical rearrangement and represents a mild and general tool for the preparation of valuable alkyl group‐functionalized heterocyclic compounds. magnified image