A Convenient Procedure for the Synthesis of Substituted 4-Methylaminocoumarins

Abstract

3-Bromo-7-methoxy-4-methylcoumarin and 3-bromo-4,7-dimethylcoumarin give a mixture of the corresponding 3-aminocoumarins and 4aminomethylcoumarins upon the reaction with a number of secondary amines.In addition, the reaction of 7-methoxy-and 7-methyl-4-bromomethylcoumarins with secondary diamines affords the corresponding N,N`-dicoumarinmethyldiamine.