Concepedia

RETRACTED ARTICLE: Mirt2 functions in synergy with miR-377 to participate in inflammatory pathophysiology of Sjögren's syndrome

Miaomiao Xin, Hongda Liang, Hongyue Wang, Dawei Wen, Liqin Wang, Mingshu Sun, Jibo Wang

Artificial Cells Nanomedicine and Biotechnology · 2019 · 16 citations · 25 references

DOIFull text

Open access

Concepts

Abstract

Mirt2 was elevated in IFN-γ-treated SGECs and then up-regulated miR-377 in response to inflammatory lesions. Mechanically, in synergy with miR-377 Mirt2 blocked IFN-γ-evoked activation of NF-κB and JAK/STAT signalling pathway.

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