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Sodium Hypochlorite Pentahydrate (NaOCl·5H2O) Crystals as an Extraordinary Oxidant for Primary and Secondary Alcohols

DOI

50

Citations

0

References

2014

Year

Yoshikazu Kimura, Tomohide Okada, Tomotake Asawa, Yukihiro Sugiyama, Masayuki Kirihara, Toshiaki Iwai
Synlett

Abstract

Sodium hypochlorite pentahydrate crystals containing less free sodium hydroxide and sodium chloride have been developed as an improved oxidant. Primary and secondary alcohols have been oxidized to the corresponding aldehydes and ketones with ­NaOCl·5H<sub>2</sub>O in the presence of TEMPO/Bu<sub>4</sub>NHSO<sub>4</sub>. This new oxidation method does not require pH adjustment and is applicable to sterically hindered secondary alcohols.