Chemical and Pharmaceutical Bulletin · 1997 · 32 citations · 0 references
Natural SciencesChemistryMarine BiologyMarine EcologyMarine Invertebrate BiologyOrganic ChemistryMarine Bioactive CompoundsMarine Natural Product BiosynthesisMarine Natural ProductsBioactive Compounds From Marine SpongesMarine Sponge MetabolitesMarine SterolsMass Spectral Data AnalysisSponge SystematicsSponges-derived Metabolites
Topsentinols A-J (1-10), new 7-hydroxysterols with unusual polyalkylated side chains were obtained from the Okinawan marine sponge Topsentia sp. and their structures elucidated on the basis of spectral data. Side chains containing the 22E-24-isopropenyl-25-methyl-22-ene group (in 1, 6) and the 22Z-24-isopropyl-22-ene group (in 2, 7) are unprecedented.