Bromopyrrole Alkaloids from the Jamaican Sponge Didiscus Oxeata

Abstract

Three bromopyrrole alkaloids (1–3) were isolated from the acetone extracts of Didiscus oxeata during chemical and biological investigation of Caribbean and Indo-Pacific marine sponges. The structures were established by spectroscopic methods. Mukanadin D (3) was obtained for the first time as a naturally-occurring C 11 bromopyrrole alkaloid.