Catalysis by β‐Cyclodextrin Hydrate – Synthesis of 2,2‐Disubstituted 2<i>H</i>‐Chromenes in Aqueous Medium

Abstract

Abstract A cost‐effective, operationally simple and eco‐compatible protocol for the one‐pot synthesis of photochromic pyrans by the reaction of propargyl alcohols as well as propargyl ethers with differently substituted phenols under ambient atmosphere in aqueous medium has been developed using β‐cyclodextrin hydrate as an efficient, recyclable and stable catalyst. This is the first report where β‐cyclodextrin hydrate acted as a catalyst for an organic transformation but β‐cyclodextrin alone failed. magnified image