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A New Simple Route to the Thieno[2,3-<i>b</i>]indole Ring System
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2008
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Chemical EngineeringNew Simple RouteEngineeringRing TheoryElectrophilic RecyclizationEffective MethodOrganic ChemistryChemistrySynthesis MethodAnhydrous Alcl3Synthetic ChemistryEnantioselective SynthesisNatural Product Synthesis
A simple and effective method has been elaborated for the synthesis of thieno[2,3-b]indole ring system. It is based on the electrophilic recyclization of 2-alkyl-5-(2-isothiocyanoaryl)furans in the presence of anhydrous AlCl3.