Water-soluble conjugated polymer with near-infrared absorption for synergistic tumor therapy using photothermal and photodynamic activity

Abstract

A novel near-infrared absorbing photo-agent based on a water-soluble conjugated polymer (PTDBD) is reported for synergetic photothermal/photodynamic therapy with single near-infrared light (808 nm) irradiation. In vitro and in vivo studies demonstrated the superior therapeutic effect of the single NIR-irradiated PTT/PDT by using PTDBD.