Highly Selective Oxidative Cleavage of β-Cyclodextrin−Epoxide/Aziridine Complexes with IBX in Water

Abstract

Water, an environmentally friendly reaction medium, has been utilized for the reaction of IBX with various epoxides 1 and aziridines 2 as their beta-cyclodextrin complexes to afford for the first time alpha-hydroxyketones 3 and alpha-aminoketones 4, respectively.