Publication | Closed Access
Hydroxamic Acids − An Intriguing Family of Enzyme Inhibitors and Biomedical Ligands
178
Citations
73
References
2004
Year
Hydroxamic AcidsChemical BiologyRedox BiologyMedicinal ChemistryReactive Nitrogen SpecieBiomedical LigandsBioorganometallic ChemistryStructural DiversityInhibitory ActivityBiochemistryHydroxamic Acids DealsIntriguing FamilyDrug DevelopmentPharmacologyNatural SciencesRational Drug DesignMetal ComplexesMedicineNitrosative StressDrug Discovery
Abstract This review on hydroxamic acids deals with their efficacy as inhibitors of enzymes including cyclooxygenases, their synthesis, the complexity and structural diversity of their metal complexes, and their ability to act as effective nitric oxide donors. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
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