Mild and Efficient Coupling of Diazo Compounds with Azaaromatic Systems under Solvent-Free Conditions

Abstract

Diazoesters and diazoketones undergo smooth coupling with activated quinolines and isoquinolines under extremely mild conditions to afford diazo-(2-ethoxy-2-oxoethyl)-1,2-dihydro­quinolines and -isoquinolines, respectively, in good to high yields with high selectivity.