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From Tetronic Acid and Furfural to C(4)-Halogenated, Vinylated and Formylated Furan-2(5H)-ones and Their 5-Alkoxy Derivatives
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1996
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Tetronic AcidChemical EngineeringCross-coupling ReactionEngineeringDerivative (Chemistry)Their 5-Alkoxy DerivativesKey ReactionsPalladium-catalyzed CrossOrganic ChemistryOrganometallic CatalysisCatalysisChemistryChemical DerivativeSynthetic ChemistryEnantioselective SynthesisBiomolecular Engineering
Tetronic acid and furfural have been elaborated into the title compounds. Palladium-catalyzed cross coupling with vinylstannanes and controlled ozonolysis followed by anhydrous workup are key reactions.