Asymmetric Synthesis of (−)-Indolizidine 209D via <i>B</i>-Alkyl Suzuki Coupling and Amination Reactions

Abstract

(-)-Indolizidine 209D has been synthesized using consecutive amination reactions of compound 11. The precursor was prepared concisely using B-alkyl Suzuki cross coupling of chiral homoallyl amine and vinyl iodide compounds. Reaction: see text.