A New and Convenient Method for Reduction of Oximes to Amines with NaBH₃CN In the Presence of MoCl₅/NaHSO₄·H₂O System

Abstract

Various aldoximes and ketoximes were efficiently reduced to their corresponding amines with <TEX>$NaBH_3CN$</TEX> in the presence of <TEX>$MoCl_5/NaHSO_4{\cdot}H_2O$</TEX> system. Reduction reactions were carried out in refluxing EtOH or DMF within 0.3-3.8 h to afford the amines in high to excellent yields.