Concepedia

Stereocontrolled preparation of chiral secondary α-methylene γ-lactams by addition of organozinc reagents derived from 2-(bromomethy])acrylates to imines using β-aminoalcohols as chiral auxiliaries.

Yénimégué Albert Dembelé, C. BELAUD, J. Villiéras

Tetrahedron Asymmetry · 1992 · 53 citations · 19 references

DOI

Concepts

References

19

1. A - C

Eugen Reichel · 1909 · 1.5K citations

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Studies on the reaction of α-imino esters with organometallic compounds

Yoshinori Yamamoto, Wataru Ito · Tetrahedron · 1988 · 124 citations

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Syntheses of (S)-5-substituted 4-aminopentanoic acids: a new class of .gamma.-aminobutyric acid transaminase inactivators

Richard B. Silverman, Mark A. Levy · The Journal of Organic Chemistry · 1980 · 122 citations

, , +8

Palladium-catalyzed carbonylation. A new synthesis of .alpha.-methylene .gamma.-, .delta.-, .epsilon.-lactams and lactones including bicyclic lactams of pyrrolizidine and indolizidine skeletons

Miwako Mori, Yumiko Washioka, Takao Urayama et al. · The Journal of Organic Chemistry · 1983 · 91 citations

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Synthesis of Potential Cytotoxic α-Methylene γ-Lactams

C. BELAUD, Christos Roussakis, Yves Letourneux et al. · Synthetic Communications · 1985 · 84 citations

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