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Microwave-Promoted Transformations: Fast and Chemoselective N-Acylation of Amino Alcohols Using Catalytic Amounts of Dibutyltin Oxide. Influence of the Power Output and the Nature of the Acylating Agent on the Selectivity
56
Citations
9
References
1996
Year
EngineeringOrganic ChemistryChemistryEnzymatic ModificationPower OutputBiochemistryBiocatalysisMicrowave-promoted TransformationsAmino AlcoholsCatalysisMicrowave SynthesisAcylating AgentCatalytic SynthesisBiomolecular EngineeringNatural SciencesEnzyme Catalysis1,3-Amino AlcoholsMolecular CatalysisSynthetic Chemistry
The influence of the nature of the acylating agent and the power output on the chemoselectivity of the microwave-mediated acylation of 1,2- and 1,3-amino alcohols catalyzed by dibutyltin oxide has been studied. The method constitutes an efficient procedure for the selective N-acylation of amino alcohols.
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