An Efficient Chemoselective Synthesis of Pyrido[2,3-<i>d</i>]pyrimidine Derivatives under Microwave Irradiation

Abstract

A facile and selective synthesis of poly-substituted pyrido[2,3-d]pyrimidines is accomplished via microwave-assisted multicomponent reactions controlled by the nature of solvent. In addition, a possible mechanism accounting for the reaction is proposed.