Journal of Heterocyclic Chemistry · 2004 · 17 citations · 2 references
Life SciencesMedicinal ChemistryMicrobiologyDrug DiscoveryMedical MicrobiologyMycologyAntifungal AgentsAntifungal PharmacologyFungal BiochemistryFungal InfectionsFungal PathogenesisBiological Activity FeaturesCandida Albicans InfectionNatural Antifungal CompoundsNew Antifungal AgentsNovel Antifungal Drug Development
Abstract A series of 6‐fluoro‐4‐(5 or 7)‐chloro‐2‐(difluorobenzoyl)aminobenzothiazoles 3a‐r were prepared to investigate their potential biological activity. In this work, the results of their in vitro antifungal activity against some strains of Candida albicans are reported. It was found that some derivatives displayed antifungal activity higher than that for 3k [1a] compound already described in literature.
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Violetta Cecchetti, Arnaldo Fravolini, Renata Fringuelli et al. · Journal of Medicinal Chemistry · 1987 · 88 citations