Mauritine-K, A new antifungal cyclopeptide alkaloid from Zizyphus mauritiana

Abstract

Department of Medicinal Chemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221 005,<br> Uttar Pradesh, India<br> <em>E-mail</em>: [e-mail] <em>Fax</em>: 91-542-2367568<br> Department of Chemistry, S. G. R. P. G. College, Dobhi-222 149, Purvanchal University, Jaunpur, Uttar Pradesh, India<br> <em>Manuscript received 19 August 2006, revised 19 April 2007, accepted 13 June 2007</em> The cyclopeptide alkaloids, mauritine-K and sativanine-K have been isolated from the root bark of <em>Zizyphus mauritiana</em> and their structures established by spectral and chemical evidences. Mauritine-K is a new cyclopeptide alkaloid and sativanine-K is the first report from <em>Z</em>.<em> mauritiana</em>. Mauritine-K exhibited significant antifungal activity.