An Iodine-Promoted, Mild and Efficient Method for the Synthesis of Phenols from Arylboronic Acids

Abstract

A mild and efficient methodology for the ipso-hydroxylation of arylboronic acids to phenols has been developed using aqueous hydrogen peroxide as oxidizing agent and molecular iodine as catalyst. The reactions were performed at room temperature in short reaction time under metal-, ligand- and base-free conditions.