Concepedia

Chemotherapeutic agents. XIX. Synthesis of [1,2,4]‐Triazoloquinazolinones and related compounds as antihypertensive agents

Vishnu Ji Ram, R.C. Srimal, D. S. KUSHWAHA, L. MISHRA

Journal für praktische Chemie · 1990 · 29 citations · 4 references

DOI

Concepts

Abstract

Abstract A series of 1,2,4‐triazolo[4,3‐a]quinazolin‐5‐ones have been prepared to assess their therapeutic utility as CNS depressant, spasmolytic and hypertensive agents.

References

4

Comparative evaluation of quinazolones: a new class of hypnotics.

Gujral Ml, Saxena Pn, Tiwari Rs · PubMed · 1955 · 62 citations

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Studies on biologically active halogenated compounds. II. Chemical modifications of 6-amino-2-fluoromethyl-3-(o-tolyl)-4(3H)-quinazolinone and the CNS depressant activities of related compounds.

Junichi Tani, Yoshihisa Yamada, Takashi Ochiai et al. · Chemical and Pharmaceutical Bulletin · 1979 · 25 citations · Full text

, , +10

Synthesis and Anticonvulsant Activity of Substituted 2-Thioquinazolin-4-ones I: Preliminary Studies

Arthur C. Glasser, Louis K. Diamond · Journal of Pharmaceutical Sciences · 1971 · 19 citations

, , +9

CNS-depressant activity of some newly synthesised 4(3H)-quinazolones.

Mukerji Dd, Nautiyal, Prasad Cr et al. · PubMed · 1980 · 15 citations

, , +8