Synlett · 1993 · 37 citations · 0 references
Natural SciencesChemistryMedicinal ChemistryBiocatalysisOrganic ChemistryOrganometallic ChemistryChiral SeparationHeterocycle SynthesisHeterocyclic ChemistryHeterocyclic CompoundsOrganic SynthesisOrganometallic SynthesisAsymmetric ReductionsDesymmetrization By ReductionEnantioselective ReductionEnantioselective SynthesisKetonesProchiral Ketone Reduction
Oxazaborolidines derived in situ, from erythro 2-amino-1,2-diphenylethanol, norephedrine, or diphenylprolinol and borane, were demonstrated to be practical reagents for enantioselective reduction of prochiral ketones.